Which cutaneous manifestations are associated with complications of DM treatment

Treatment with insulin can cause local or systemic allergic reactions (itching, urticaria, seldom angioneurotic oedema, etc.); however, these are now extremely rare due to the use of the purified human insulins that are available. Lipoatrophy (localized loss of subcutaneous tissue) or lipohypertrophy (increase/thickening of subcutaneous tissue) at sites of insulin injection are also relatively rare today with the new insulins.

Oral antidiabetic medicines, and mainly sulfonylureas, may also cause allergic reactions from the skin, within 6-8 weeks from onset of

Figure 18.6. Erythema multiforme with the typical target lesions (Reprinted from Color Atlas of Dermatology, G.M. Levene, Copyright 1974, with permission from Elsevier).

treatment. These range from the simple urticaria to erythema multiforme (Figure 18.6) and its severe form (Stevens Johnson syndrome, see Figure 18.7), as well as eczema, blisters in the skin, photosensitivity, purpura and erythema nodosum.

Figure 18.7. Mouth ulcerations in Stevens-Johnson syndrome, the severe form of erythema multiforme (Reprinted from Color Atlas of Dermatology, G.M. Levene, Copyright 1974, with permission from Elsevier).
Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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