Do diabetic individuals have a higher susceptibility towards infections compared to nondiabetics

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Sufficient data do not exist to substantiate the opinion that diabetics, as a whole, have a higher susceptibility towards infections. However, some infections are more common in diabetic patients, and others present nearly exclusively in these people. Moreover, some infections have a more severe clinical course and manifest a higher frequency of complications in diabetics.

The increased susceptibility of diabetics to certain infections is due to many factors. The polymorphonuclear neutrophils of diabetics have been found to have decreased chemotactic and phagocytic abilities. Furthermore, it seems that the ability of leukocytes to counter the microorganisms after the process of phagocytosis is diminished.

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