Ldl Tg

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Statins ± resins Fibric acid derivatives

Abbreviations: HDL, high density lipoprotein; LDL, low density lipoprotein; TG, triglyceride.

a Continue ongoing management of other risk factors, including therapy for hypertension and smoking cessation.

Data from American Diabetes Association. Management of dyslipidemia in children and adolescents with diabetes. Diabetes Care 2003;26(7):2195.

modification with nutritional therapy in boys over the age of 10 and in post-menarchal girls with familial hypercholesterolemia.

Microvascular complications

Primary evaluation and routine follow-up of children who have T2DM should include monitoring for signs of microvascular complications. Urinary microalbumin excretion and renal function should be checked after the diagnosis is established and annually. A dilated retinal examination to look for retinopathy should be performed annually by a qualified physician. It is not clear how soon this examination should be implemented, however. Currently it is left to the clinician's discretion to decide when to start this screening process. Because T2DM in youth is a relatively new entity, these recommendations are not evidence based but rather stem from our experience with children who have T1DM.

Summary

T2DM has emerged as a serious public health problem in the pediatric population, with its escalating rates paralleling the epidemic of childhood obesity. A high index of suspicion is important to prompt screening in the clinical setting of high-risk youth. Screening helps in the early diagnosis and initiation of therapy in subclinical or silent cases of T2DM in youth. The objective and theory behind early diagnosis are the preservation of pancreatic beta-cell function and the prevention of the relentless decline in insulin secretion. In our efforts to treat hyperglycemia and its associated complications, however, we must remember to type 2 diabetes mellitus in youth

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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