Summary And Conclusions

Despite intensified metabolic control and antihypertensive treatment of diabetic patients, the development of diabetic nephropathy remains a serious problem. There is increasing evidence for a multifactorial pathogenesis of diabetic kidney disease, including various growth factors and cytokines as active players. This article has reviewed recent evidence for the significance of GH and VEGF in the development of experimental diabetic kidney disease. In addition, experimental data strongly suggest that GH and VEGF blockade may present new concepts in the treatment of diabetic renal complications. Future studies are warranted to fully characterize the clinical potential of GH and VEGF inhibitors as drugs for treatment of diabetic complications in general. Recent observations have suggested that there most likely in an important interaction or cross-talk among various growth factors that may promote the development of diabetic kidney disease. This would imply that strategies which involve multiple effects on the development of diabetic kidney disease may be more effective than drugs which influence one pathway. An increasing number of studies on the effects of combination of inhibitors with different points of action have the potential to provide new therapeutic strategies and experimental and clinical studies on combination therapies are expected to appear in the coming years.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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