Diabetic Glomerulopathy The diffuse lesion

This consists of a uniform widening of the mesangial regions (figure 1). It is particularly well exhibited in sections stained by periodic acid-Schiff (PAS) or by silver methenamine that display structures often described as finger-like radiations from the glomerular hilum.

Fig. 1. Diabetic glomerulopathy, diffuse type. There is a slight increase of PAS-positive material in all mesangial regions, radiating from the vascular pole (upper right). PAS-haematoxylin.

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