Consequences Of Asymptomatic Bacteria

Recently, a large study among 796 sexually active, non-pregnant women without DM (age 18-40 years old), identified ASB as a strong predictor of a subsequent symptomatic UTI [34] In (other) studies of non-diabetic patients, it was suggested that ASB can lead to recurrent UTIs, progressive renal impairment, hypertension, and an increased mortality [35], although most authors agree that ASB per se in a healthy individual causes no harm [36,37]. However, despite the high prevalence of ASB among women with DM, little is known about the consequences in this specific population [12,7]. In the study mentioned earlier, we have shown that women with DM type 2 with ASB at baseline had an increased risk of developing a UTI during the 18-month follow-up, compared to women with DM type 2 without ASB at baseline (17% without ASB versus 27% with ASB, p=0.02). In contrast, we did not find a difference in the incidence of asymptomatic UTI between DM type 1 women with and without ASB. However, a more interesting finding was that women with DM type 1 and ASB had tendency to a faster decline in renal function than those without ASB (relative increase in creatinin 4.6% versus 1.5%, p=0.2) [28]. If longer follow-up studies, as ongoing in our center, show that ASB contributes to the development of diabetic nephropathy, this would have important consequences. Diabetes now accounts for 35% of all new cases of end-stage renal disease in the United States, and persons with DM make up the fastest growing group of renal dialysis and transplant recipients [38,39].

Diabetes Sustenance

Diabetes Sustenance

Get All The Support And Guidance You Need To Be A Success At Dealing With Diabetes The Healthy Way. This Book Is One Of The Most Valuable Resources In The World When It Comes To Learning How Nutritional Supplements Can Control Sugar Levels.

Get My Free Ebook

Post a comment