Cardiovascular Risk Factors In Microalbuminuria Familial Predisposition

Positive family histories of hypertension or CVD in the non-diabetic parents are related to the development of albuminuria in the diabetic proband emphasising the shared predisposition to these two conditions. These associations hold true for both Type 1 and Type 2 diabetes after adjustment for age, sex and duration of diabetes [56, 57]. There is also some evidence for a familial predisposition to develop microalbuminuria in association with essential hypertension. Children with one hypertensive parent have a higher AER than children of a normotensive parent while normotensive adults with at least one hypertensive parent have elevated AER compared to normotensive adults with a negative family history for arterial hypertension [58].

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