Pioglitazone and Macrovascular Disease

A recent study [31] investigated the effects of intensive glycemic control on macrovascular disease. It was a prospective, randomized controlled trial involving over 5,000 type 2 diabetics with preexisting macrovascular complications. They were randomized to receive either 45-mg pioglitazone or placebo for approximately 2.5 years. Pioglitazone was shown to reduce the risk of all cause mortality, non-fatal myocardial infarction (excluding silent myocardial infarction), and stroke by approximately 16% as compared with placebo. There was, however, an increase in the rate of heart failure in the pioglitazone group (11%) versus placebo (8%). The study concluded that pioglitazone improved cardiovascular outcomes in type 2 diabetics with high cardiovascular risk profiles.

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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