Leaky Gut Syndrome Holistic Treatments Ebooks Catalog
Diets with a high glycemic response may also increase the ability of Candida to grow, thereby increasing the likelihood of developing dysbiosis and the resulting inflammatory cascade. Reducing foods high in sugars and starch limits a primary source of fuel for the gastrointestinal yeast, Candida albicans, which is known to release toxins, such as oxylipins, that damage intestinal cells and compromise the integrity of intestinal linings. Gut flora imbalance and the subsequent compromised integrity of protective mucosal linings is the primary reason dietary lectins can become a problem. Of the food lectins, grain cereal lectins (especially wheat), dairy lectins, and legume lectins (especially peanut lectin and soybean lectin) are the most common ones associated with reports of aggravation of inflammatory signaling in the gut and in the body. In individuals who are displaying any of the signs and symptoms of gut flora imbalance as discussed above, it is critical to eliminate intake of...
Unless related to omission of insulin therapy, DKA is usually precipitated by coexisting illness. The most common factor is infection ranging from trivial viral infections to full-blown septicaemia. Other precipitating factors are cardiovascular events (myocardial infarction, stroke), gastrointestinal disease, inflammatory diseases, pancreatitis, trauma and major surgery, alcohol abuse and drugs (e.g. glucocorticoids). All of these factors induce insulin resistance due to stress hormone responses. Furthermore, poor appetite and food deprivation will often lead the patient to take less insulin, erroneously of course. In this context gastrointestinal disease with nausea and vomiting poses a specific problem and it may be necessary to admit such
Considerable research indicates that a disruption of the normal bacteria inhabiting the gastrointestinal tract can increase the likelihood of allergic sen-sitization during infancy. Taking antibiotic treatments for ear infections is a common method of destroying normal gut bacteria. Taking probiotic (good bacteria) supplements can reduce the damage when antibiotics must be taken.
The cycle of inflammatory chemistry that is activated through chronic stress and cortisol release, leaky gut, environmental stressors (such as chemical preservatives, plastics, and heavy metals), obesity, thyroid dysfunction, and immune system imbalances causes chronic imbalances in blood glucose homeostatis, eventually lead to type 2 diabetes. This progression to diabetes and its metabolic consequences has also been linked in clinical studies with the development of cancer 7, 8 . Researchers have known for decades that cancer cells consume more glucose than normal cells. All cells use both oxidative phosphorylation and glycolysis pathways for energy (ATP) but rely overwhelmingly on oxidative phosphorylation, switching to glycolysis at times of oxygen deprivation. Cancer cells, however, have been reported to exhibit increased glycol-ysis due in part to mitochondrial respiration injury and hypoxia. A shift in energy production from oxidative phosphorylation to glycolysis - the...
Hyperglycaemia is usually present in DKA, but it is important to realise that DKA not infrequently presents with normal or modestly elevated glucose concentrations 15 . This may particularly be the case during caloric deprivation due to, for example, gastrointestinal disease. Hyperglycaemia is caused by a combination of lack of insulin and excess of stress hormones, leading to insulin resistance. In the liver this increases gluconeo-genesis and hepatic glucose production. It is unlikely that the kidney plays any significant role in the initial stages of DKA 16 . The ensuing high glucose levels generate a high flux state with increased peripheral glucose disposal, but the increased mass action of glucose is generally insufficient to compensate fully. Muscle glucose metabolism is characterised by low insulin levels and insulin resistance because of high levels of stress hormones, high levels of free fatty acids and varying degrees of dehydration.
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