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-20 -10 0 10 20 30 40 50 4-Week reduction in glucagon60 min (pg/ml)

FIGURE 3 Inhibition of glucagon secretion after a test meal in patients with type 2 diabetes treated with Vildagliptin (LAF237). (Upper panel) Correlation between the 60-min glucagon levels and the 120-min glucose levels after ingestion of breakfast after 4 weeks of treatment with placebo (n=19) or LAF237 (vildagliptin) at 100 mg daily (n=18) in subjects with type 2 diabetes. (Lower panel) Correlation between the 4-week reduction in 60-min glucagon and the 4-week reduction in 120-min glucose after treatment with LAF237 at 100 mg daily (n=18) in subjects with type 2 diabetes. Linear correlations are shown. Source. From Ref. 91.

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