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ap £ 0.05 (univariate association, diabetes subgroup vs. corresponding controls).

Note: People with insulin-dependent diabetes mellitus (IDDM) have increased prevalence of constipation and/or use of laxatives and decreased prevalence of heartburn. Prevalence of dyspepsia is not greater in diabetics than in controls.

Abbreviations: A Neuro = autonomic neuropathy; IDDM = insulin-dependent diabetes mellitus; NIDDM = noninsulin-dependent diabetes mellitus; P Neuro = peripheral neuropathy.

Source: Reproduced from Ref. 5.

GI symptoms. The Psychosomatic Symptom Checklist score is significantly associated with the reporting of GI tract symptoms (15). Several mechanisms interact to produce disordered gastrointestinal function in diabetes. These are best documented in the function of the stomach; hence the following section addresses the mechanisms that are relevant in diabetic gastroparesis.

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