Glucagon serves as the primary signal for hepatic glucose production and release. While glucagon is normally secreted in times of fasting and suppressed after meals, in patients with diabetes there is often inadequate suppression or even a paradoxical increase of glucagon secretion following meals, contributing to postprandial hyperglycemia (21). Pramlintide suppresses this abnormal rise in postprandial glucagon (21). Given that insulin-induced hypoglycemia is a major concern for patients with diabetes, and that pramlintide is
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.