Abbreviations: ACEi, angiotensin-converting-enzyme inhibitor; ARB, angiotensin ll-receptor-blocker; CD, cochrane database; NE, not estimateable; STO, subtotals only; TIMS, totals not selected. Source: From Ref. 68.
when compared with patients receiving amlodipine or chlorthalidone. A serious weakness of ALLHAT is the fact that 50% of the patients in the ACEi group were either not receiving the medication or were receiving a dose so low (only 10 mg lisinopril) that renoprotection might not be expected in the study (73,74).
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