It is considered an orphan drug and is available in liquid form for the treatment of insulinoma. Short-term use of this agent for the treatment of hypertension has been associated with hyperglycemia and hyperosmolar non-ketotic coma (38). Direct inhibition of insulin secretion may be the primary mechanism responsible for the hyperglycemia (39) Other possible mechanisms may include direct stimulation of hepatic glucose production, increased epinephrine secretion, decreased insulin sensitivity and increased insulin clearance (40).
Was this article helpful?
Do You Suffer From High Blood Pressure? Do You Feel Like This Silent Killer Might Be Stalking You? Have you been diagnosed or pre-hypertension and hypertension? Then JOIN THE CROWD Nearly 1 in 3 adults in the United States suffer from High Blood Pressure and only 1 in 3 adults are actually aware that they have it.