Maintenance Of Wholebody Glucose And Ffa Homeostasis

Glucose and FFA Homeostasis

In the postabsorptive (fasting) state, energy is derived primarily from the breakdown of endogenous fat stores, whereas hepatic, and, to a lesser extent, renal endogenous glucose production maintains blood glucose levels for utilization by organs such as the brain. Fatty acids derived from lipoprotein breakdown or released as FFAs from adipose tissue are oxidized as the main source of energy (Fig. 1 and Color Plate 2, following p. 34). Postprandially there is a shift toward storage of energy metabolites, mediated to a large extent by

A Post-absorptive/fasting period

B Postprandial period

Insulin-independent glucose uptake

Insulin-independent glucose uptake

Brain

Brain

Insulin action

f \ Fasting

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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