The pathogenesis of diabetic neuropathy is complex and it is important to understand the underlying pathology leading to the complication in order to best tailor treatment for each individual patient. It is unlikely that reversing any single mechanism will prove sufficient for reversing nerve damage. Several drugs, such as antioxidant, PKC inhibitors and nerve growth factors can have effects on multiple systems that are compromised in diabetic neuropathy, yet even those may not be enough in and of themselves to completely restore neurological function. Combination therapy may prove to be the best long term approach, and studies of those combinations should prove revealing as to the relative roles of metabolic dysfunction, microvascular insufficiency and autoim-munity in the diabetic neuropathy patient population.
Key Words: Antioxidant; PKC inhibitors and nerve growth factors; VEGF.
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This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.