Introduction

The neuropathies are among the most common of the long-term complications of diabetes, affecting up to 50-60% of patients. Progressive loss of nerve fibres might affect both somatic and autonomic divisions, producing a wide range of symptoms and signs, which can be assessed using an array of measures, that differ when used for screening as opposed to detailed quantification for research or when assessing the benefits of therapeutic intervention. For the latter, two major types of end point are utilized: (1) those which assess symptoms for defining efficacy in painful diabetic neuropathy and (2) those which assess neurological deficits. An alteration in symptoms does not necessarily reflect an improvement in nerve function. Furthermore, tests which might accurately detect structural repair on repeat nerve or skin biopsy might not necessarily translate to improved neuronal function and vice versa. Thus, although there is considerable enthusiasm to develop new therapies for both symptoms and deficits, the criteria used to determine therapeutic efficacy are varied and lacking consensus.

From: Contemporary Diabetes: Diabetic Neuropathy: Clinical Management, Second Edition Edited by: A. Veves and R. Malik © Humana Press Inc., Totowa, NJ

Supplements For Diabetics

Supplements For Diabetics

All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.

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