Diabetic neuropathy is the most common neuropathy in industrialized countries, with a remarkable range of clinical manifestations. More than 80% of the patients with clinical diabetic neuropathy have a distal sy mmetrical form, with predominant or isolated sensory and autonomic manifestations (1,2). In the others, and usually in association with symptomatic or latent distal symmetrical sensory polyneuropathy, patients with diabetes might develop a focal neuropathy that includes cranial nerve involvement, limb and truncal neuropathies, and proximal diabetic neuropathy (PDN) of the lower limbs. In this group of neuropathies the disorder tends to occur both in men and women more than 50 years of age, most with longstanding type 1 and type 2 diabetes. The long-term prognosis of focal neuropathy is good in most cases, but sequelae occur. The occurrence of focal neuropathy in patients with diabetes requires first to exclude a nerve lesion owing to a superimposed cause by appropriate investigations. Then, to consider the occurrence of nondiabetic neuropathies more common

From: Contemporary Diabetes: Diabetic Neuropathy: Clinical Management, Second Edition Edited by: A. Veves and R. Malik © Humana Press Inc., Totowa, NJ

in patients with diabetes, before concluding that the patient is suffering from a focal diabetic neuropathy and discussing which treatment, if any, is needed in addition to control of diabetes.

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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