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transcutaneous P02 20 kg higher body weight 0.3 high ankle-arm index Poor vision 13 mmHg orthostatic BP fall

1.2 (1.1-1.4) 0.8 (0.7-1) 0.9 (1.4-2.6) 1.2 (1.1-1.5)

VPT, vibration pressure threshold; SWF, Semmes-Weinstein monofilament; TcP02, transcutaneous oxygen pressure.

subjects enrolled. Independent risk factors for foot ulceration included foot insensitivity to the 5.07 monofilament (RR 2.2, 95% CI 1.5-3.1), past history of amputation (RR 2.8, 95% CI 1.8-4.3), past history of foot ulceration (RR 1.6,95% CI 1.2-2.3), insulin use (RR 1.6, 95% CI1.1-2.2), Charcot deformity (RR 3.5, 95% CI 1.2-9.9), 15 mmHg lower dorsal foot transcutaneous PO2 (RR 0.8,95% CI 0.7-0.9), 20 kg higher body weight (RR 1.2, 95% CI 1.1-1.4), 0.3 higher ankle-arm index (RR 0.8, 95% CI 0.7-1), poor vision (RR 0.9, 95% CI 1.4-2.6), and 13 mmHg orthostatic BP fall (RR 1.2, 95% CI 1.1-1.5) (58). This study and others emphasized the importance of screening for loss of protective sensation in daily clinical practice in order to identify those subjects at risk who require intensive education and other interventions in order to prevent foot ulceration.

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