Preface

Geoffrey Boner and Mark E Cooper

Over the past half-century, it has become abundantly clear that one of the major medical problems facing the modern world is diabetes mellitus. This systemic disease, with a plethora of complications and comorbid conditions, is a major cause of mortality and morbidity and is associated with a large economic burden on the patients themselves, their families and the health-care systems of most countries.

Diabetic nephropathy is a major complication of diabetes and is today one of the major causes of endstage renal failure in many developed and undeveloped nations. Moreover, diabetic nephropathy is associated with many of the other macro- and microvascular complications of diabetes. As diabetes and its complications are treated by general practitioners, family physicians and internists, as well as by many specialist physicians, the treatment is often fragmented and not coordinated. Coordination of treatment is especially important in those diabetic patients with renal involvement. The past few years have seen the emergence of several therapeutic regimens that may prevent the development of diabetic nephropathy and slow the progression of this disorder.

The time is thus opportune for publishing a book that contains a description of the development of diabetes mellitus, renal involvement and other comorbid conditions, and the latest therapeutic regimens. We are pleased that many senior investigators have contributed to this book, which should provide basic information on diabetes, diabetic nephropathy and some other complications, and at the same time provide data on recent therapeutic trials and accepted therapeutic regimens. The subject matter should be of interest to general practitioners, family physicians, internal physicians, endocrinologists and nephrologists as well as nurses and dietitians involved in the care of diabetic patients. We hope that the coming years will provide additional information in this important field and that there will be room for publishing more information on diabetic nephropathy.

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