Given that a loss in endogenous HGF production by hyperglycemia may be causative for the histological and clinical manifestations of diabetic renal disease, administration of exogenous HGF (or its gene) would inhibit or reverse the progression of diabetic renal injury. Using a model of DN, we obtained evidence that HGF may be a therapeutic factor for inhibiting TGF-P upregulation and renal fibrosis. We will discuss herein the relationship among molecular, histological, and clinical changes to understand the therapeutic effect of HGF in DN.
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.