Contents

Preface vii

Contributors ix

1 Diabetic Ketoacidosis in Adults 1

Definition 4

Mortality 5

Precipitating factors 6

Pathogenesis 7

Fluid and electrolyte depletion 12

Clinical features 14

Diagnosis 16

Treatment 22

Complications of diabetic ketoacidosis in adults 30

Further reading 31

2 Diabetic Ketoacidosis in Childhood 33

Introduction 34

Definition 35

Pathophysiology 35

Differential diagnosis 37

Management 39

Further reading 53

3 Hyperosmolar Non-ketotic Hyperglycaemia 55

Pathogenesis 56

Diagnosis 60

Treatment 62

Further reading 71

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